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Motif ID: FOS_FOS{B,L1}_JUN{B,D}.p2

Z-value: 4.023

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr18_+_21452981	36.591	NM_000227 NM_001127718	LAMA3	laminin, alpha 3
chr1_+_183155393	24.976		LAMC2	laminin, gamma 2
chr12_+_13349601	24.247	NM_001423	EMP1	epithelial membrane protein 1
chr12_+_13349720	21.920		EMP1	epithelial membrane protein 1
chr1_+_223889253	21.602	NM_001146068	CAPN2	calpain 2, (m/II) large subunit
chr1_+_153003677	19.540	NM_003125	SPRR1B	small proline-rich protein 1B
chr1_+_183155173	18.400	NM_005562 NM_018891	LAMC2	laminin, gamma 2
chr1_+_183155361	17.009		LAMC2	laminin, gamma 2
chr12_-_52886971	15.520	NM_005554	KRT6A	keratin 6A
chr18_+_61442611	15.419	NM_003784	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr3_-_151034514	15.282	NM_023915	GPR87	G protein-coupled receptor 87
chr19_-_39264144	15.211	NM_002307	LGALS7 LGALS7B	lectin, galactoside-binding, soluble, 7 lectin, galactoside-binding, soluble, 7B
chr1_-_95007139	15.101	NM_001178096 NM_001993	F3	coagulation factor III (thromboplastin, tissue factor)
chr17_-_39768939	13.968	NM_005557	KRT16	keratin 16
chr1_-_209824641	13.872	NM_001017402	LAMB3	laminin, beta 3
chr3_-_149095413	12.095		TM4SF1	transmembrane 4 L six family member 1
chr6_+_83072922	11.790	NM_006670	TPBG	trophoblast glycoprotein
chr2_-_216259197	11.418		FN1	fibronectin 1
chr3_-_149095517	11.258	NM_014220	TM4SF1	transmembrane 4 L six family member 1
chr3_-_149095458	11.151		TM4SF1	transmembrane 4 L six family member 1
chr17_-_39743085	10.880	NM_000526	KRT14	keratin 14
chr6_-_138428477	10.539	NM_022121	PERP	PERP, TP53 apoptosis effector
chr18_+_61144143	10.305	NM_002639	SERPINB5	serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr17_-_39675078	10.065	NM_002275	KRT15	keratin 15
chr4_+_169753105	9.976	NM_001166110	PALLD	palladin, cytoskeletal associated protein
chr1_+_27189628	9.516	NM_006142	SFN	stratifin
chr18_+_61554938	9.418	NM_001143818 NM_002575	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr11_+_101983170	9.016	NM_001195045	YAP1	Yes-associated protein 1
chr3_-_149095333	8.950		TM4SF1	transmembrane 4 L six family member 1
chr19_-_51523272	8.906	NM_002776 NM_001077500	KLK10	kallikrein-related peptidase 10
chr1_-_153538305	8.904	NM_005978	S100A2	S100 calcium binding protein A2
chr19_+_39279849	8.899	NM_001042507	LGALS7B	lectin, galactoside-binding, soluble, 7B
chr17_-_39780762	8.820	NM_000422	KRT17	keratin 17
chr1_-_152009440	8.426		S100A11	S100 calcium binding protein A11
chr1_-_152009406	8.357		S100A11	S100 calcium binding protein A11
chr11_-_102668822	8.168		MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr11_-_6341708	8.152	NM_145040	PRKCDBP	protein kinase C, delta binding protein
chr11_-_102668892	8.145	NM_001145938 NM_002421	MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr7_+_48128225	7.967	NM_181597	UPP1	uridine phosphorylase 1
chr2_-_166650770	7.784	NM_004482	GALNT3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr3_-_32022734	7.539		OSBPL10	oxysterol binding protein-like 10
chr3_+_30647901	7.520	NM_001024847 NM_003242	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)
chr3_-_32023237	7.399	NM_001174060 NM_017784	OSBPL10	oxysterol binding protein-like 10
chr13_-_38172862	7.261	NM_001135934 NM_001135935 NM_001135936 NM_006475	POSTN	periostin, osteoblast specific factor
chr10_+_17270469	7.103		VIM	vimentin
chr11_-_2950593	7.085	NM_003311	PHLDA2	pleckstrin homology-like domain, family A, member 2
chr12_-_106533810	7.063	NM_014840	NUAK1	NUAK family, SNF1-like kinase, 1
chr1_+_152956563	6.930	NM_001199828 NM_005987	SPRR1A	small proline-rich protein 1A
chr16_+_56642477	6.909	NM_005953	MT2A	metallothionein 2A
chr6_+_121756744	6.839	NM_000165	GJA1	gap junction protein, alpha 1, 43kDa
chr1_+_35246789	6.833	NM_024009	GJB3	gap junction protein, beta 3, 31kDa
chr20_-_6104056	6.768	NM_017671	FERMT1	fermitin family member 1
chr1_-_207205996	6.742	NM_001083924 NM_023938	C1orf116	chromosome 1 open reading frame 116
chr7_+_116312412	6.711	NM_000245 NM_001127500	MET	met proto-oncogene (hepatocyte growth factor receptor)
chr11_-_118134986	6.682		MPZL2	myelin protein zero-like 2
chr13_+_78109808	6.452	NM_001160706 NM_003843 NM_144777	SCEL	sciellin
chr11_-_8739398	6.406		ST5	suppression of tumorigenicity 5
chr1_+_223900226	6.380		CAPN2	calpain 2, (m/II) large subunit
chr1_+_35220647	6.361	NM_005268	GJB5	gap junction protein, beta 5, 31.1kDa
chr10_+_17270257	6.283	NM_003380	VIM	vimentin
chr11_-_118135197	6.227	NM_005797 NM_144765	MPZL2	myelin protein zero-like 2
chr1_+_156084565	6.136		LMNA	lamin A/C
chr1_-_152009467	6.100		S100A11	S100 calcium binding protein A11
chr21_-_36421586	6.038	NM_001754	RUNX1	runt-related transcription factor 1
chr1_+_223900212	5.939		CAPN2	calpain 2, (m/II) large subunit
chr7_-_107643330	5.925	NM_002291	LAMB1	laminin, beta 1
chr1_+_156084541	5.920		LMNA	lamin A/C
chr21_-_36421630	5.822		RUNX1	runt-related transcription factor 1
chr11_+_394199	5.800	NM_007183	PKP3	plakophilin 3
chr11_-_118134956	5.758		MPZL2	myelin protein zero-like 2
chr10_+_121410751	5.746	NM_004281	BAG3	BCL2-associated athanogene 3
chr1_-_152009490	5.649	NM_005620	S100A11	S100 calcium binding protein A11
chr6_-_134496833	5.594		SGK1	serum/glucocorticoid regulated kinase 1
chr11_-_65667858	5.468		FOSL1	FOS-like antigen 1
chr16_+_57662301	5.449	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr10_+_121410891	5.340		BAG3	BCL2-associated athanogene 3
chr5_+_52776479	4.933		FST	follistatin
chr11_+_35639734	4.895	NM_014344	FJX1	four jointed box 1 (Drosophila)
chr5_+_52776408	4.892		FST	follistatin
chr5_+_140868721	4.853	NM_018929 NM_032407	PCDHGC5	protocadherin gamma subfamily C, 5
chr1_+_152881022	4.852	NM_005547	IVL	involucrin
chr6_-_10419786	4.845	NM_001042425	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chrX_+_135251795	4.818	NM_001167819	FHL1	four and a half LIM domains 1
chr12_+_78225068	4.708	NM_014903	NAV3	neuron navigator 3
chr1_+_32043745	4.706	NM_001204415	TINAGL1	tubulointerstitial nephritis antigen-like 1
chr17_+_73717515	4.664	NM_000213 NM_001005731	ITGB4	integrin, beta 4
chr17_-_7493389	4.638	NM_006942	SOX15	SRY (sex determining region Y)-box 15
chr7_-_93519990	4.606	NM_006528	TFPI2	tissue factor pathway inhibitor 2
chr20_+_19867075	4.598	NM_001242581	RIN2	Ras and Rab interactor 2
chr11_-_65667809	4.545		FOSL1	FOS-like antigen 1
chr9_-_110252045	4.513	NM_004235	KLF4	Kruppel-like factor 4 (gut)
chr11_-_65667860	4.512	NM_005438	FOSL1	FOS-like antigen 1
chr20_+_4666796	4.383	NM_000311 NM_001080121 NM_001080122 NM_183079 NM_001080123	PRNP	prion protein
chrX_-_10851808	4.377	NM_033290	MID1	midline 1 (Opitz/BBB syndrome)
chr10_+_121411042	4.344		BAG3	BCL2-associated athanogene 3
chr13_-_110438896	4.248	NM_003749	IRS2	insulin receptor substrate 2
chr21_-_27543134	4.164	NM_000484 NM_001136129 NM_001136130 NM_001204301 NM_001204302 NM_001204303 NM_201413 NM_201414	APP	amyloid beta (A4) precursor protein
chr19_-_44174497	4.110	NM_001005376 NM_001005377 NM_002659	PLAUR	plasminogen activator, urokinase receptor
chr1_+_150480486	4.100	NM_001202858 NM_004425 NM_022664	ECM1	extracellular matrix protein 1
chr11_+_394238	4.099		PKP3	plakophilin 3
chr1_+_156084458	4.070	NM_005572 NM_170707 NM_170708	LMNA	lamin A/C
chr6_-_134497069	4.048	NM_001143678	SGK1	serum/glucocorticoid regulated kinase 1
chr20_+_33759773	3.984	NM_006404	PROCR	protein C receptor, endothelial
chr21_-_27543445	3.982	NM_001136131	APP	amyloid beta (A4) precursor protein
chr10_+_121411071	3.972		BAG3	BCL2-associated athanogene 3
chr17_+_73717556	3.959		ITGB4	integrin, beta 4
chr1_+_150480584	3.916		ECM1	extracellular matrix protein 1
chr5_-_1882764	3.830	NM_016358	IRX4	iroquois homeobox 4
chr22_-_45608232	3.829		KIAA0930	KIAA0930
chr4_-_114900802	3.824	NM_024590	ARSJ	arylsulfatase family, member J
chr17_+_79651035	3.824		HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr18_+_55888838	3.739		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr15_+_41136178	3.717	NM_003710 NM_181642	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr11_-_120008801	3.706		TRIM29	tripartite motif containing 29
chr18_+_61637262	3.682	NM_001031848 NM_002640 NM_198833	SERPINB8	serpin peptidase inhibitor, clade B (ovalbumin), member 8
chr3_+_100238063	3.653		TMEM45A	transmembrane protein 45A
chr17_+_74380943	3.643		SPHK1	sphingosine kinase 1
chr18_+_55888799	3.631		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr3_-_123339178	3.552		MYLK	myosin light chain kinase
chr19_-_43969723	3.529	NM_014400	LYPD3	LY6/PLAUR domain containing 3
chr1_-_154943001	3.525	NM_001130040 NM_183001	SHC1	SHC (Src homology 2 domain containing) transforming protein 1
chr1_+_81771844	3.516		LPHN2	latrophilin 2
chr10_+_123872440	3.502		TACC2	transforming, acidic coiled-coil containing protein 2
chr19_-_19051112	3.493	NM_001145722 NM_001145721	HOMER3	homer homolog 3 (Drosophila)
chr17_+_74381419	3.478		SPHK1	sphingosine kinase 1
chr8_+_32504250	3.452	NM_013959	NRG1	neuregulin 1
chr5_+_73109342	3.446	NM_001244364	RGNEF	190 kDa guanine nucleotide exchange factor
chr21_-_27512668	3.420	NM_001136016	APP	amyloid beta (A4) precursor protein
chr17_+_21191347	3.414	NM_002756	MAP2K3	mitogen-activated protein kinase kinase 3
chr1_-_153521717	3.387	NM_002960	S100A3	S100 calcium binding protein A3
chr17_+_79651042	3.364		HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr21_-_27543044	3.351		APP	amyloid beta (A4) precursor protein
chr1_+_186798031	3.340	NM_024420	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr15_+_41136622	3.322	NM_001032367	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr6_+_30856462	3.320	NM_001202521 NM_001202522 NM_013994	DDR1	discoidin domain receptor tyrosine kinase 1
chr21_+_30517897	3.301		C21orf7	chromosome 21 open reading frame 7
chr11_+_35198199	3.275		CD44	CD44 molecule (Indian blood group)
chr17_+_74381186	3.266	NM_001142602	SPHK1	sphingosine kinase 1
chr17_+_73717596	3.255		ITGB4	integrin, beta 4
chr1_+_44398991	3.240	NM_001136215 NM_057090 NM_057091	ARTN	artemin
chr12_-_54813002	3.175		ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr15_-_60690115	3.163	NM_001002857 NM_001002858 NM_001136015 NM_004039	ANXA2	annexin A2
chr11_+_706103	3.136	NM_022772	EPS8L2	EPS8-like 2
chr20_-_43977023	3.117	NM_002999	SDC4	syndecan 4
chr11_-_33744497	3.078	NM_001127227	CD59	CD59 molecule, complement regulatory protein
chr17_+_79651072	3.069		HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr1_+_223900061	3.062	NM_001748	CAPN2	calpain 2, (m/II) large subunit
chr1_-_244006471	3.056	NM_005465 NM_181690	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
chr2_-_85641153	3.052		CAPG	capping protein (actin filament), gelsolin-like
chr19_-_51472816	3.027	NM_002774	KLK6	kallikrein-related peptidase 6
chr1_+_152486977	3.010	NM_019060	CRCT1	cysteine-rich C-terminal 1
chr20_-_36152952	3.009	NM_001167823	BLCAP	bladder cancer associated protein
chr17_+_79650961	3.003	NM_004712	HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr4_+_74606222	2.990	NM_000584	IL8	interleukin 8
chr2_-_85637486	2.948	NM_001747	CAPG	capping protein (actin filament), gelsolin-like
chr2_-_85641128	2.927		CAPG	capping protein (actin filament), gelsolin-like
chr12_-_8815370	2.901	NM_003480	MFAP5	microfibrillar associated protein 5
chr5_-_134914968	2.899	NM_004887	CXCL14	chemokine (C-X-C motif) ligand 14
chr2_-_65593866	2.897	NM_001128210	SPRED2	sprouty-related, EVH1 domain containing 2
chr15_-_56209305	2.872	NM_198400	NEDD4	neural precursor cell expressed, developmentally down-regulated 4
chr3_+_187930720	2.870	NM_005578	LPP	LIM domain containing preferred translocation partner in lipoma
chr1_-_153029987	2.868	NM_005988	SPRR2A	small proline-rich protein 2A
chr1_+_36621751	2.868	NM_018067	MAP7D1	MAP7 domain containing 1
chr16_-_122573	2.852	NM_022450	RHBDF1	rhomboid 5 homolog 1 (Drosophila)
chr10_+_121411086	2.846		BAG3	BCL2-associated athanogene 3
chr2_-_85637473	2.843		CAPG	capping protein (actin filament), gelsolin-like
chr3_-_48632592	2.826	NM_000094	COL7A1	collagen, type VII, alpha 1
chr7_+_23286384	2.774		GPNMB	glycoprotein (transmembrane) nmb
chr6_-_84140854	2.732	NM_002395	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic
chr12_-_54812936	2.724		ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr12_-_54813010	2.686	NM_002205	ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr21_-_36421578	2.661		RUNX1	runt-related transcription factor 1
chr5_+_35856990	2.648	NM_002185	IL7R	interleukin 7 receptor
chr5_+_36608430	2.631	NM_001166695	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_-_73316782	2.627		RAB11FIP5	RAB11 family interacting protein 5 (class I)
chr7_+_23286420	2.609		GPNMB	glycoprotein (transmembrane) nmb
chr16_+_66968319	2.605	NM_003869 NM_198061	CES2	carboxylesterase 2
chr5_+_140729723	2.601	NM_018922 NM_032095	PCDHGB1	protocadherin gamma subfamily B, 1
chr11_+_123986103	2.598	NM_001130142 NM_014622 NM_198315	VWA5A	von Willebrand factor A domain containing 5A
chr3_-_123339423	2.580	NM_053031 NM_053032	MYLK	myosin light chain kinase
chr6_+_106959729	2.567	NM_001624	AIM1	absent in melanoma 1
chr20_-_6103562	2.557		FERMT1	fermitin family member 1
chr10_+_102792161	2.553		SFXN3	sideroflexin 3
chr1_+_26606621	2.550		SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3
chr1_-_86043932	2.534	NM_001134445	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr1_-_152297678	2.522	NM_002016	FLG	filaggrin
chr6_-_84140758	2.474		ME1	malic enzyme 1, NADP(+)-dependent, cytosolic
chr7_+_23286277	2.465	NM_001005340 NM_002510	GPNMB	glycoprotein (transmembrane) nmb
chr5_+_52776263	2.465	NM_006350 NM_013409	FST	follistatin
chr1_+_156084579	2.459		LMNA	lamin A/C
chr12_-_53343607	2.456		KRT8	keratin 8
chr10_+_5136589	2.384		AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr19_-_44174271	2.373		PLAUR	plasminogen activator, urokinase receptor
chr7_+_23286390	2.368		GPNMB	glycoprotein (transmembrane) nmb
chr3_-_49395697	2.365		GPX1	glutathione peroxidase 1
chr15_+_22892723	2.361		CYFIP1	cytoplasmic FMR1 interacting protein 1
chr1_-_153013593	2.359	NM_006945	SPRR2D	small proline-rich protein 2D
chr10_-_30024594	2.353	NM_003174	SVIL	supervillin
chr16_+_66968360	2.353		CES2	carboxylesterase 2
chr20_+_44637539	2.338	NM_004994	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
3.64	1.39e-11	GO:0009888	tissue development
7.47	1.85e-10	GO:0008544	epidermis development
1.80	1.03e-05	GO:0048856	anatomical structure development
28.87	2.11e-05	GO:0031581	hemidesmosome assembly
2.06	4.91e-05	GO:0048513	organ development
1.80	6.72e-05	GO:0048731	system development
2.85	9.91e-05	GO:0007155	cell adhesion
2.85	9.91e-05	GO:0022610	biological adhesion
1.70	1.13e-04	GO:0007275	multicellular organismal development
1.65	1.21e-04	GO:0032502	developmental process
1.52	2.86e-04	GO:0032501	multicellular organismal process
13.23	7.67e-04	GO:0007044	cell-substrate junction assembly
2.45	8.86e-04	GO:0009611	response to wounding
14.44	2.86e-03	GO:0031424	keratinization
3.45	3.22e-03	GO:0060429	epithelium development
2.74	3.61e-03	GO:0042060	wound healing
7.56	1.08e-02	GO:0010951	negative regulation of endopeptidase activity
6.27	1.44e-02	GO:0031099	regeneration
8.42	1.92e-02	GO:0030216	keratinocyte differentiation
1.79	2.26e-02	GO:0030154	cell differentiation
5.61	3.60e-02	GO:0010466	negative regulation of peptidase activity
2.14	4.33e-02	GO:0042127	regulation of cell proliferation
1.74	4.71e-02	GO:0048869	cellular developmental process
4.82	4.97e-02	GO:0030162	regulation of proteolysis

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
21.79	2.76e-06	GO:0001533	cornified envelope
1.64	2.85e-05	GO:0005886	plasma membrane
4.11	4.12e-05	GO:0005578	proteinaceous extracellular matrix
3.76	4.15e-05	GO:0031012	extracellular matrix
1.62	5.84e-05	GO:0071944	cell periphery
3.04	9.31e-05	GO:0030054	cell junction
5.04	1.53e-04	GO:0070161	anchoring junction
4.66	3.95e-04	GO:0005911	cell-cell junction
1.74	2.10e-03	GO:0044459	plasma membrane part
23.52	3.09e-03	GO:0043256	laminin complex
5.40	3.32e-03	GO:0044420	extracellular matrix part
2.15	3.85e-03	GO:0044421	extracellular region part
5.96	4.04e-03	GO:0005882	intermediate filament
5.24	4.34e-03	GO:0045111	intermediate filament cytoskeleton
4.41	8.54e-03	GO:0005912	adherens junction
1.90	9.02e-03	GO:0005856	cytoskeleton
1.79	9.38e-03	GO:0005576	extracellular region
6.39	2.21e-02	GO:0005604	basement membrane
14.12	3.06e-02	GO:0005605	basal lamina
5.79	4.15e-02	GO:0016327	apicolateral plasma membrane

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
8.54	5.20e-05	GO:0004867	serine-type endopeptidase inhibitor activity
5.62	3.43e-04	GO:0004866	endopeptidase inhibitor activity
5.53	4.14e-04	GO:0030414	peptidase inhibitor activity
5.39	5.44e-04	GO:0061135	endopeptidase regulator activity
2.72	8.31e-04	GO:0005198	structural molecule activity
4.45	4.00e-03	GO:0061134	peptidase regulator activity